USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: ARPC2_HUMAN USC-OGP 2-DE database:  ARPC2_HUMAN ARPC2_HUMAN General information about the entry View entry in simple text format Entry name ARPC2_HUMAN Primary accession number O15144 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Actin-related protein 2/3 complex subunit 2; AltName: Full=Arp2/3 complex 34 kDa subunit; Short=p34-ARC;. Gene name Name=ARPC2 Synonyms=ARC34 ORFNames=PRO2446 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-0991: pI=6.92; Mw=28259 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1252: pI=7.02; Mw=30801 Cross-references UniProtKB/Swiss-Prot O15144; ARPC2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name ARPC2_HUMAN Primary accession number O15144 Secondary accession number(s) Q92801 Q9P1D4 Sequence was last modified on  January 1, 1998 (version 1) Annotations were last modified on  March 15, 2017 (version 153) Name and origin of the protein Description RecName: Full=Actin-related protein 2/3 complex subunit 2; AltName: Full=Arp2/3 complex 34 kDa subunit; Short=p34-ARC; Gene name Name=ARPC2 Synonyms=ARC34 ORFNames=PRO2446 Encoded on Name=ARPC2; Synonyms=ARC34; ORFNames=PRO2446 Keywords Acetylation; Actin-binding; Cell junction; Cell projection; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Reference proteome; Synapse; Synaptosome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF006085; AAB64190.1; -; mRNA EMBL U50523; AAC50874.1; ALT_FRAME; mRNA EMBL BT006898; AAP35544.1; -; mRNA EMBL BC000590; AAH00590.1; -; mRNA EMBL AF116702; AAF71122.1; ALT_INIT; mRNA CCDS CCDS2410.1; -; . RefSeq NP_005722.1; NM_005731.3; . RefSeq NP_690601.1; NM_152862.2; . UniGene Hs.529303; -; . ProteinModelPortal O15144; -; . SMR O15144; -; . BioGrid 115415; 82; . DIP DIP-33197N; -; . IntAct O15144; 33; . MINT MINT-5000439; -; . STRING 9606.ENSP00000295685; -; . DrugBank DB08235; N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide; . iPTMnet O15144; -; . PhosphoSitePlus O15144; -; . SwissPalm O15144; -; . OGP O15144; -; . EPD O15144; -; . MaxQB O15144; -; . PaxDb O15144; -; . PeptideAtlas O15144; -; . PRIDE O15144; -; . TopDownProteomics O15144; -; . DNASU 10109; -; . Ensembl ENST00000295685; ENSP00000295685; ENSG00000163466; . Ensembl ENST00000315717; ENSP00000327137; ENSG00000163466; . GeneID 10109; -; . KEGG hsa:10109; -; . CTD 10109; -; . DisGeNET 10109; -; . GeneCards ARPC2; -; . HGNC HGNC:705; ARPC2; . HPA CAB001994; -; . HPA HPA008352; -; . MIM 604224; gene; . neXtProt NX_O15144; -; . OpenTargets ENSG00000163466; -; . PharmGKB PA24999; -; . eggNOG KOG2826; Eukaryota; . eggNOG ENOG410YKF6; LUCA; . GeneTree ENSGT00390000016794; -; . HOGENOM HOG000212535; -; . HOVERGEN HBG050580; -; . InParanoid O15144; -; . KO K05758; -; . OMA FPRHFAN; -; . OrthoDB EOG091G0BUH; -; . PhylomeDB O15144; -; . TreeFam TF315006; -; . Reactome R-HSA-2029482; Regulation of actin dynamics for phagocytic cup formation; . Reactome R-HSA-3928662; EPHB-mediated forward signaling; . Reactome R-HSA-5663213; RHO GTPases Activate WASPs and WAVEs; . Reactome R-HSA-8856828; Clathrin-mediated endocytosis; . SIGNOR O15144; -; . ChiTaRS ARPC2; human; . GeneWiki ARPC2; -; . GenomeRNAi 10109; -; . PRO PR:O15144; -; . Proteomes UP000005640; Chromosome 2; . Bgee ENSG00000163466; -; . CleanEx HS_ARPC2; -; . ExpressionAtlas O15144; baseline and differential; . Genevisible O15144; HS; . GO GO:0015629; C:actin cytoskeleton; TAS:ProtInc; . GO GO:0005885; C:Arp2/3 protein complex; IDA:FlyBase; . GO GO:0031252; C:cell leading edge; IEA:Ensembl; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0005768; C:endosome; IEA:Ensembl; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005925; C:focal adhesion; IDA:UniProtKB; . GO GO:0036195; C:muscle cell projection membrane; IEA:Ensembl; . GO GO:0043005; C:neuron projection; IEA:UniProtKB-SubCell; . GO GO:0045202; C:synapse; IEA:UniProtKB-KW; . GO GO:0005200; F:structural constituent of cytoskeleton; IDA:FlyBase; . GO GO:0034314; P:Arp2/3 complex-mediated actin nucleation; IDA:FlyBase; . GO GO:0048013; P:ephrin receptor signaling pathway; TAS:Reactome; . GO GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome; . GO GO:0061024; P:membrane organization; TAS:Reactome; . GO GO:0006928; P:movement of cell or subcellular component; TAS:ProtInc; . GO GO:0010592; P:positive regulation of lamellipodium assembly; IMP:UniProtKB; . GO GO:1900026; P:positive regulation of substrate adhesion-dependent cell spreading; IEA:Ensembl; . InterPro IPR007188; ARPC2; . PANTHER PTHR12058; PTHR12058; 1; . Pfam PF04045; P34-Arc; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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